Danish authorities say an intravenous drug user who injected heroin and died has tested positive for anthrax. The Health Ministry suspects the drug was contaminated with the bacillus anthracis strain of anthrax. The 55-year-old addict died Sunday. 0 Comments Weigh InCorrections? Personal Post Terrorism is not suspected, and the health ministry says there is no risk of contagion because the bacteria cannot be passed from person to person. Anthrax is a deadly disease that can be treated with antibiotics if caught early. Officials said Monday they will compare the case to two similar deaths in Germany in June. Last week, German officials said there may be a link between contaminated heroin found in Germany and an anthrax outbreak in Scotland in 2009 and 2010, which left 10 people dead.
Smokers could one day be immunised against nicotine so they gain no pleasure from the habit, according to researchers in the US.
They have devised a vaccine that floods the body with an antibody to assault nicotine entering the body.
A study in mice, published in Science Translational Medicine, showed levels of the chemical in the brain were reduced by 85% after vaccination.
Years of research are still needed before it could be tested on people.
However, lead researcher Prof Ronald Crystal is convinced there will be benefits.
"As far as we can see, the best way to treat chronic nicotine addiction from smoking is to have these Pacman-like antibodies on patrol, clearing the blood as needed before nicotine can have any biological effect."
New approach
Other "smoking vaccines" have been developed that train the immune system to produce antibodies that bind to nicotine - it is the same method used to vaccinate against diseases. The challenge has been to produce enough antibodies to stop the drug entering the brain and delivering its pleasurable hit.
Scientists at Weill Cornell Medical College have used a completely different approach, a gene-therapy vaccine, which they say is more promising.
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Prof Ronald CrystalWeill Cornell Medical CollegeIf they start smoking again, they will receive no pleasure from it due to the nicotine vaccine, and that can help them kick the habit”
A genetically modified virus containing the instructions for making nicotine antibodies is used to infect the liver. This turns the organ into a factory producing the antibodies.
The research team compared the amount of nicotine in the brains of normal mice with those that had been immunised. After being injected with nicotine, the vaccinated mice had nicotine levels 85% lower.
It is not known if this could be repeated in humans or if this level of reduction would be enough to help people quit.
Prof Crystal said that if such a vaccine could be developed then people "will know if they start smoking again, they will receive no pleasure from it due to the nicotine vaccine, and that can help them kick the habit".
He added: "We are very hopeful that this kind of vaccine strategy can finally help the millions of smokers who have tried to stop, exhausting all the methods on the market today, but find their nicotine addiction to be strong enough to overcome these current approaches."
'Impressive and intriguing'
There are also issues around the safety of gene therapy in humans that will need to be answered.
Professor of genetics at the University of Kent, Darren Griffin, said the findings were "impressive and intriguing with great potential" but cautioned there were still many issues which needed addressing.
He said the main issue "is whether the observed biochemical effects in lab mice genuinely translate to a reduced addiction in humans given that such addictions can be both physical and psychological".
Dr Simon Waddington, from University College London, said: "The technology underpinning gene therapy is improving all the time and it is encouraging to see these preliminary results that indicate it could be used to address nicotine addiction, which is damaging to the nation's health and a drain on the health service economy."
If such a vaccine was developed it could also raise ethical questions about vaccinating people, possibly in childhood, before they even started smoking.
Coca-Cola and Pepsi contain minute traces of alcohol, scientific research published in France has revealed. The revelation will cause concern among those who chose the carbonated soft drink for religious, health or safety reasons. According to tests carried out by the Paris-based National Institute of Consumption (INC) more than half of leading colas contain the traces of alcohol. Can't beat the real thing: The revelation will cause concern among those who chose the carbonated soft drink for religious, health or safety reasons These include the brand leaders Coca-Cola and Pepsi Cola, while it is mainly only cheap supermarket versions of the drink which are alcohol-free. ‘60 Million Consumers’, the French magazine, publishes the results of the tests in its latest issue. They suggest that the alcohol levels are as low as 10mg in every litre, and this works out at around 0.001 per cent alcohol.
After the recent stream of disturbing news reports of people eating others' flesh, Hornaday Manufacturing has released bullets that promise to ‘make dead permanent.’
The ammunition, branded as Zombie Max offers Proven Z-Max bullets, is live ammunition, but is actually only intended for use on targets – not people.
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The Walking Dead: Hornady Manufacturing has started selling Zombie bullets, 'just in case'; it is live ammunition
Attacks: Carl Jacquneaux, left, who was arrested for allegedly biting another man's face and Brandon De Leon, right, who allegedly tried to bite two policemen while threatening to eat them
Hornaday spokesman Everett Deger told WWJ Newsradio 950 that the company’s president has a love of zombie culture – including popular shows like the Walking Dead – and was inspired to make the bullets in honour of the cultural phenomenon.
ON CLOUD NINE: BATH SALTS BY ANOTHER NAME... WITH STRONG COMPULSIONS TO REDOSE
The 'bath salts' sold under the name Cloud Nine are likely to be stimulant drugs such MPDV or ephedrine.
'Bath salts' does not refer to a single chemical, but instead to a range of synthetic drugs that can be sold legally in the U.S. as long as they are not marked for human consumption – hence the misleading name.
Drugs such as MPDV are highly potent stimulants, similar to some amphetamines, and in MPDV's case particularly, cause a strong compulsion to 'redose' with more of the drug.
In high doses, such drugs can cause violent and unpredictable behaviour, and terrifying hallucinations – and the compulsion to take more of the drug continues, even once the 'high' has begun to make the user feel bad.
Various different compounds use the name 'Cloud Nine', and it's still not confirmed which exact chemical was in the drug reported to have caused these attacks, but some reports have pointed the finger at MPDV.
The chemical is already illegal in Florida – although other 'bath salts' remain perfectly legal in the state.
‘We decided just to have some fun with a marketing plan that would allow us to create some ammunition designed for that…fictional world,’ he told the radio station.
Mr Deger noted that the bullets are some of the ammunition company’s most popular products.
The news comes as two more cannibal attacks have been reported in the US as police warn of a dangerous new mind-altering drug called Cloud Nine.
Last week Rudy Eugene - who is believed to have taken the over-the-counter ecstasy-like drug - growled at officers as he chewed off most of a homeless man's face before being shot dead by Miami police.
Since then two further incidents have been linked to the substance, which is part of a new line of 'bath salts'.
More...
- Revealed: Miami cannibal's girlfriend shows herself in public for the first time and claims her beau was carrying a BIBLE before the attack
- Caught on camera: The moment woman driver rams into pedestrian and travels for hundreds of yards with him clinging on 'because of her hormones'
- Revealed: The videos 'Canadian cannibal' sent to his 'fans' while on the run from police - and one of them contains infamous song from American Psycho
The second occurred on Saturday when a snarling homeless man, identified as Brandon De Leon, threatened to eat two officers, echoing the Miami attack.
A third incident took place in Louisiana where Carl Jacquneaux, 43, bit off a chunk of his victim's face. Miami police have issued a warning about Cloud Nine and told their officers to exercise extreme caution when dealing with homeless men who appear to be acting unusually.
Police investigating the case of Rudy Eugene, who ate the face off a homeless man, say as well as being naked, he was carrying a bible.
Some pages had been ripped out of the book and were found close by, according to CBS Miami. A preliminary toxicology examination has also found that the 31-year-old had been smoked cannabis shortly before the incident.
They were forced to fit 21-year-old De Leon with a Hannibal Lecter-style mask after he was arrested for disturbing the peace in North Miami Beach. When put in a police cruiser De Leon slammed his head against the plexiglass divider and shouted at officers, 'I'm going to eat you', NBC Miami reported.
He then growled, gnashed his teeth and tried to bite the hand of an officer attempting to treat his head wounds.
'Brandon growled and opened and closed his jaw, slamming his teeth like an animal would,' the report said. Miami police said they believe he was on a cocktail of drugs, including Cloud Nine.
In a second case Carl Jacquneaux, 43, is accused of attacking Todd Credeur at his home in Scott, Louisiana, over the weekend after he became upset following a domestic issue.
Victim: Todd Credeur, though in shock, managed to spray his attacker in the face with wasp spray to stop him from eating any more of his face
Scene: Todd Creneur was attacked while working on the yard outside his home in Scott, Louisiana
KATC reported that Mr Credeur was working in his front yard when he was attacked.
Scott Assistant Police Chief Kert Thomas said: 'During the attack, the suspect bit a chunk of the victim's face off.'
Mr Credeur reportedly managed to spray Jacquneaux in the face with wasp spray to stop him from eating any more of his face.
Jacquneaux then allegedly left the home and went to another man's home where he held him at knife point and stole a hand gun. This is where police found him and arrested him.
A friend of the victim said she believes Jacquneaux was under the influence of Cloud Nine, which is the same drug which is believed to have been taken by the 'Miami Cannibal' Rudy Eugene.
Eugene ate the face of homeless man Ronald Poppo in Miami last week and a police memo to officers has highlighted the dangers surrounding the drug's use.
It warned the De Leon case 'bears resemblance to an incident that occurred in the city of Miami last week, when a male ate another man's face'.
'Please be careful when dealing with the homeless population during your patrols.'
Police have suggested Eugene was under the influence of the synthetic stimulant usually sold in drug paraphanelia shops.
Cloud Nine is 'addictive and dangerous', the memo said, part of a 'disturbing trend in which new drugs are sold in the guise of household products'.
The drug, which is also as Ivory Wave in the U.S., comes in harmless-looking packets, police said, adding that it is illegal in Britain and Australia.
Crazed attack: Cloud Nine, which is the same drug which is believed to have been taken by the 'Miami Cannibal' Rudy Eugene (left) when he savagely attacked 65-year-old Ronald Poppo (right)
The potentially addictive drug stimulates the central nervous system and symptoms include heart palpitations, nausea, hallucinations, paranoia and erratic behaviour.
The series of shocking incidents began on May 26 when a naked Eugene encountered his victim, 65-year-old Ronald Poppo, who was sleeping in the shade on elevated train tracks.
In surveillance footage from the nearby Miami Herald building, Eugene was seen struggling with the naked homeless man, throwing him to the ground and then tearing into his face with his teeth as cars and bicycles sped by.
About 18 minutes into the attack, an officer appeared on the scene and yelled at Eugene to stop, but the 31-year-old just growled at him and continued chewing Poppo’s face.
The officer then opened fire on Eugene, shooting him to death.
Horrific attack: The spot on MacArthur Causeway when a man was killed after chewing the face off a stranger
Disfigured: Poppo, here on a stretcher, miraculously survived the attack, but was left without a nose, mouth or eyes
Poppo remains in critical condition at Jackson Memorial Hospital with his nose, mouth and eyes torn off. He faces months of treatment to rebuild his features and psychological care.
Controversially this week the scene of the attack on Poppo has been Miami added to sites visited by a tourist tour's itinerary.
The famous Miami Mystery & Mayhem: Crime Tour tour led by Miami-Dade College professor Dr Paul George will stop on the road that connects downtown Miami to popular South Beach.
Dr Paul told the South Florida Business Journal: 'Horrible as it was, it is part of our history. Currently, our tour takes us over the causeway right past the site, so this fits well.'
In a completely separate case not involving the drug, Canadian Luka Rocco Magnotta has been sent back to his country from Germany after an international manhunt.
He is alleged to have killed his partner, Jun Lin, before eating parts of his body then chopping it to pieces that were then posted to different authorities. Mr Lun's head has not yet been found.
'ZOMBIE APOCALYPSE': RECENT CANNIBAL ATTACKS ACROSS AMERICA
Since Rudy Eugene attacked and ate the face of homeless man Ronald Poppo on May 26 in Miami, Florida, while allegedly high on 'bath salts' there has been a spate of similar attacks.
The 'Miami Cannibal' case shocked the nation after police had to shoot dead Eugene when he refused to stop eating his victim's face off. Poppo is now recovering in hospital with horrific injuries.
Brandon DeLeon, 21, was high on drugs and drunk on Four Loko on June 2 when he tried to bite off a police officer’s hand after he was arrested for disturbing customers in a Miami fast food restaurant.
The homeless man repeatedly banged his head against the patrol car’s Plexiglas and yelled, ‘I’m going to eat you.’
At the police station, De Leon tried to bite the officer who was taking his blood pressure and tending to his self-inflicted wounds. The police report noted that he 'growled and opened and closed his jaw slamming his teeth like an animal would.'
Carl Jacquneaux, 43, is accused of attacking Todd Credeur at his home in Scott, Louisiana, over the weekend after he became upset following a domestic issue.
Mr Credeur reportedly managed to spray Jacquneaux in the face with wasp spray to stop him from eating any more of his face.
A friend of the victim said she believes Jacquneaux was under the influence of Cloud Nine, which is the same drug which is believed to have been taken by the 'Miami Cannibal' Rudy Eugene.
Alex Kinyua, 21, a college student, used a knife to carve up Kujoe Bonsafo Agyei-Kodie, 37, before eating his heart out and parts of his brain.
He then took to his social networking site to boast about it to his friends saying: 'Are you strong enough to endure ritual HBCU mass human sacrifices around the country and still be able to function as human beings?'
He referred to the tragic shootings at Virginia Tech and 'other past university killings around the country' and warned 'ethnic cleansing is the policy, strategy and tactics that will affect you, directly or indirectly in the coming months.'
A mind-altering drug banned in Britain two years ago is being blamed for the spate of cannibal attacks in America.
Narcotic Cloud Nine was blamed for the attack when Rudy Eugene ate 75% of homeless man Ronald Poppo’s face in Miami last month.
Horrific images surfaced of the attack that only ended once police shot and killed 31-year-old Eugene.
Mr Poppo is still recovering from his injuries in hospital.
Police are now warning people to stay away from Cloud Nine – also known as ‘bath salts’ - after two similar attacks were reported.
The most recent prompted an internal memo to police warning officers the case “bears resemblance to an incident that occurred in the city of Miami last week, when a male ate another man’s face”.
The memo called the synthetic drug “addictive and dangerous” and said it was part of a “disturbing trend in which new drugs are sold in the guise of household products”.
It added: “Please be careful when dealing with the homeless population during your patrols.”
Rudy Eugene, 31: Ate 75% of a man's face in Miami before being shot dead
Brandon De Leon, 21: Tried to bite two police officers after he was arrested in North Miami Beach
Carl Jacquneaux, 43: Bit a man's face in Scott, Louisiania. Wasp spray was used to end the attack
Alex Kinyua, 21: Accused of eating the heart and brain of friend in Maryland
Horror: Film cannibal Hannibal Lecter
During the latest attack homeless Brendon De Leon threatened to eat two Miami police officers and had to be fitted with a Hannibal Lecter-style mask to prevent him carrying his threats out.
He had been arrested for disturbing the peace in North Miami Beach while high on drugs and put in a police cruiser when he slammed his head against the plexiglass divider and shouted: “I’m going to eat you” to officers before growling and baring his teeth.
Miami police said they believe he was on a cocktail of drugs including Cloud Nine.
In another case, Carl Jacquneaux, 43, was accused of attacking Todd Credeur in his front garden in Scott, Louisiana, over the weekend after being upset over a domestic issue while under the influence of what is said to be bath salts.
Jacquneaux bit Mr Credeur before being sprayed in the face with wasp spray.
Scott Assistant Police Chief Kert Thomas said: “During the attack, the suspect bit a chunk of the victim’s face off.”
Jacquneaux was then said to have left the property and gone to another man’s home where he held him at knife-point and stole a handgun before being apprehended by police.
The drug, which is also known as Ivory Wave, was blamed for several deaths in Britain during 2010 before being banned. It is also illegal in Australia.
The potentially addictive drug stimulates the central nervous system and symptoms include heart palpitations, nausea, hallucinations, paranoia and erratic behaviour and is often sold in plain packaging with the contents purporting to be harmless.
Sergio Villarreal, known as El Grande (Big One) because of his height, is facing charges of drug trafficking and money laundering in a court in Texas. Police arrested Mr Villarreal in a raid east of Mexico City two years ago. He is alleged to have been the top lieutenant in the once-powerful Beltran Leyva drug cartel, accused of smuggling large quantities of cocaine, marijuana and heroin to the US. A former policeman, Mr Villarreal is alleged to have worked for a number of criminal organizations before joining the drugs cartel led by Arturo Beltran Leyva. Mr Beltran Leyva was shot and killed by the Mexican navy in December 2009, sparking a brutal fight for control of the cartel. His brother Hector took over the leadership of the cartel. Mexican authorities say continued infighting and the arrest of all of its major leaders except for the still-fugitive Hector Beltran Leyva have led to the cartel being disbanded.
Unemployed people suspected of suffering from alcoholism or drug addiction will have their benefits cut if they refuse treatment for their condition, the work and pensions secretary, Iain Duncan Smith, will signal on Wednesday. In a sign of the government's new benefits regime, which lies at the heart of Duncan Smith's cost-cutting welfare changes, staff in Jobcentre Plus offices will be encouraged to cut the jobseeker's allowance of claimants who reject treatment for addiction. The new rules will come into place in October 2013 when the universal credit, which is designed to wrap benefits into one payment, is introduced. A new claimant contract lies at the heart of the universal credit reforms. Claimants will have to sign a contract in which they agree to look for work in exchange for an undertaking from the government to support them while they do so. Government sources said the contract would allow Jobcentre Plus staff to say that a suspected addict is in breach of their commitments if they refuse help for alcoholism or drug addiction. Duncan Smith will give a flavour of the new rules when he addresses an event in parliament organised by Alcoholics Anonymous (AA). He will say: "The outdated benefits system fails to get people off drugs and put their lives on track. We have started changing how addicts are supported, but we must go further to actively take on the devastation that drugs and alcohol can cause. "Under universal credit we want to do more to encourage and support claimants into rehabilitation for addiction and starting them on the road to recovery and eventually work. Getting people into work and encouraging independence is our ultimate goal. Universal credit will put people on a journey towards a sustainable recovery so they are better placed to look for work in future and we will be outlining our plans shortly." It is understood that the work and pensions secretary will not make a formal announcement on Wednesday of the powers that will be handed to Jobcentre Plus staff. Duncan Smith wants to use the event to focus on what he regards as the positive work AA does in helping to treat alcoholism. A government source said: "Iain wants to focus on the brilliant work Alcoholics Anonymous does in changing people's lives. He really wants to encourage people who have drink problems to go to AA for treatment. It will transform their lives and will help them into work." The source said Duncan Smith believes it is right to give jobcentre staff powers to cut benefits if an addict refuses treatment because they can detect signs of trouble. The source said: "The universal credit will allow staff in Jobcentre Plus offices to say: this person has been unemployed for some time. The staff know if people are addicted to alcohol. They know the people they are dealing with. "But we want this to be positive and to be about signposting people to superb organisations that can help them. This is about changing their lives. It is very important to support addicts into the workplace." But if claimants refuse they will have their benefits docked. "There will be sanctions," the source said, citing cuts to the jobseeker's allowance as an example. Ministers believe that one indicator Jobcentre Plus staff can use to see whether a claimant is an addict is the amount of times they apply for a crisis loan. "If you are applying for that up to 10 times a year then that is a sign of a chaotic life," one source said. Analysis by the Department of Work and Pensions shows that almost 40,000 people claim incapacity benefit with alcoholism declared as their "primary diagnosis". Of these, 13,500 have been claiming for a decade or more. There are about 160,000 "dependent drinkers" in England who receive one or more of the main benefits. There are 1m violent crimes a year that are related to alcoholism and 1.2m admissions to hospitals a year related to alcoholism. Universal credit is the most important element of Duncan Smith's welfare reforms, developed during his years in opposition through his Centre for Social Justice, which is designed to achieve his central goal of encouraging people into work. It will integrate tax credits and out-of-work benefits into one payment, with the aim of smoothing the transition to work. Labour has given the universal credit a cautious welcome, though it has taken issue with the scale of benefit cuts. Lord Low of Dalston, the vice-president of the Royal National Institute of Blind People who sits as a crossbencher, told peers this year: "Though it has some very sensible and progressive things at its core, in the shape of the universal credit, nevertheless it goes too far to most people's consciences in the way in which it takes vital support away from some of the most needy in our society."
Eight American soldiers died of overdoses involving heroin, morphine or other opiates during deployments in Afghanistan in 2010 and 2011, according to U.S. Army investigative reports. The overdoses were revealed in documents detailing how the Army investigated a total of 56 soldiers, including the eight who fell victim to overdoses, on suspicion of possessing, using or distributing heroin and other opiates. At the same time, heroin use apparently is on the rise in the Army overall, as military statistics show that the number of soldiers testing positive for heroin has grown from 10 instances in fiscal year 2002 to 116 in fiscal year 2010. Army officials didn't respond to repeated requests for comment on Saturday. But records from the service's Criminal Investigation Command, obtained by the conservative legal group Judicial Watch, provided glimpses into how soldiers bought drugs from Afghan juveniles, an Afghan interpreter and in one case, an employee of a Defense Department contractor, who was eventually fired. The drug use is occurring in a country that is estimated to supply more than 90% of the world's opium, and the Taliban insurgency is believed to be stockpiling the drug to finance their activities, according to a 2009 U.N. study. While the records show some soldiers using heroin, much of the opiate abuse by U.S. soldiers in Afghanistan involves prescription drugs such Percocet, the Army documents show. Judicial Watch obtained the documents under the Freedom of Information of Act and provided them to CNN. Spokesman Col. Gary Kolb of the International Security Assistance Force, the NATO-led command in Afghanistan, verified the documents to CNN on Saturday. One fatal overdose occurred in June 2010 at Forward Operating Base Blessing, after a soldier asked another soldier to buy black tar opium from a local Afghan outside the base's entry control point. The first soldier died after consuming the opium like chewing tobacco and smoking pieces of it in a cigarette, the documents show. The reports even show soldier lingo for the drug -- calling it "Afghani dip" in one case where three soldiers were accused of using the opiate, the Army investigative reports show. The United States has 89,000 troops in Afghanistan. The U.S. death toll since the September 11, 2001, attacks that triggered the war has risen to more than 1,850, including 82 this year, according to the U.S. Department of Defense and U.S. Central Command. Tom Fitton, president of Judicial Watch, said his group was interested in soldiers' drug use partly because the risk was present during the Vietnam War. "You never want to see news of soldiers dying of drug use in Afghanistan," Fitton said. "Our concern is, will the military treat this as the problem that it is, and are the families of the soldiers aware of the added risk in this drug-infested country? "There is a dotted line between the uses. Prescription abuse can easily veer into heroin drug use," Fitton added. "Afghanistan is the capital of this opiate production and the temptation is great there and the opportunity for drug use all the more." The group is concerned that "there hasn't been enough public discussion, and we would encourage the leadership to discuss or talk about this issue more openly," Fitton said. In one case, a soldier bought heroin and the anti-anxiety drug Xanax from five "local national juveniles at multiple locations on Camp Phoenix, Afghanistan, and consumed them," one report states. Soldiers also distributed heroin, Percocet and other drugs among themselves, according to the reports. Another soldier fatally overdosed in December 2010 after taking several drugs, including morphine and codeine, though the drugs were not prescribed for him, the Army documents show. One female soldier broke into the Brigade Medical Supply Office at Forward Operating Base Shank and stole expired prescription narcotics including morphine, Percocet, Valium, fentanyl and lorazepam, the documents show. The investigative reports show soldiers using other drugs, including steroids and marijuana, and even hashish that was sold to U.S. servicemen by the Afghan National Army and Afghan National Police personnel, the reports state.
Scientists have known for a while that the active ingredient in cannabis was a chemical called delta-9-tetrahydrocannabinol, or THC for short. Ingesting or smoking THC has a wide range of effects, from the psychoactive "getting high" to the physiological relief of pain and swelling. It also acts as both a stimulant and depressant. How could one substance do all that?
Meet the cannabinoid receptor
In the 1980s and 90s, researchers identified cannabinoid receptors, long, ropy proteins that weave themselves into the surfaces of our cells and process THC. They also process other chemicals, many of them naturally occurring in our bodies. Once we'd discovered these receptors, we knew exactly where THC was being processed in our bodies and brains, as well as what physical systems it was affecting. Scattered throughout the body, cannabinoid receptors come in two varieties, called CB1 and CB2 - most of your CB1 receptors are in your brain, and are responsible for that "high" feeling when you smoke pot. CB2 receptors, often associated with the immune system, are found all over the body. THC interacts with both, which is why the drug gives you the giggles and also (when interacting with the immune system) reduces swelling and pain.
Cannabinoid receptors evolved in sea squirts about 500 million years ago; humans and many other creatures inherited ours from a distant ancestor we share with these simple sea creatures. THC binds to receptors in animals as well as humans, with similar effects.
Tasty, tasty, tasty
Cannabis notoriously makes people hungry - even cancer patients who had lost all desire to eat.One study showed that cancer patients who thought food smelled and tasted awful suddenly regained an ability to appreciate food odors after ingesting a THC compound. There are CB1 receptors in your hypothalamus, a part of your brain known to regulate appetite, and your body's own cannabinoids usually send the "I'm hungry" message to them. But when you ingest THC, you artificially boost the amount of cannabinoids sending that message to your hypothalamus, which is why you get the munchies.
Understanding this process has actually led to a new body of research into safe diet drugs that would block those cannabinoid receptors. That way, your hypothalamus wouldn't receive signals from your body telling it to eat, and would reduce hunger cravings in dieters.
What you're forgetting
What's happening in your brain when smoking pot makes you forget what you're saying in the middle of saying it? According to the book Marijuana and Medicine (National Academies Press):
One of the primary effects of marijuana in humans is disruption of short-term memory. That is consistent with the abundance of CB1 receptors in the hippocampus, the brain region most closely associated with memory. The effects of THC resemble a temporary hippocampal lesion.
That's right - smoking a joint creates the effect of temporary brain damage.
What happens is that THC shuts down a lot of the normal neuroprocessing that goes on in your hippocampus, slowing down the memory process. So memories while stoned are often jumpy, as if parts are missing. That's because parts literally are missing: Basically you are saving a lot less information to your memory. It's not that you've quickly forgotten what's happened. You never remembered it at all.
A bit of the old timey wimey
Cannabis also distorts your sense of time. THC affects your brain's dopamine system, creating a stimulant effect. People who are stoned often report feeling excited, anxious, or energetic as a result. Like other stimulants, this affects people's sense of time. Things seem to pass quickly because the brain's clock is sped up. At the same time, as we discussed earlier (if you can remember), the drug slows down your ability to remember things. That's because it interferes with the brain's acetylcholine system, which is part of what helps you store those memories in your hippocampus. You can see that system's pathway through the brain in red in the illustration at left.
In an article io9 published last year about the neuroscience of time, we noted:
The interesting thing about smoking pot is that marijuana is one of those rare drugs that seems to interact with both the dopamine and the acetylcholine system, speeding up the former and slowing down the latter. That's why when you get stoned, your heart races but your memory sucks.
It's almost as if time is speeding up and slowing down at the same time.
Addiction and medicine
Some experts call cannabis a public health menace that's addictive and destroys lives by robbing people of ambition. Other experts call it a cure for everything from insomnia to glaucoma, and advocate its use as a medicine. The former want it to be illegal; the latter want it prescribed by doctors. Still other groups think it should be treated like other intoxicants such as alcohol and coffee - bad if you become dependent on it, but useful and just plain fun in other situations.
What's the truth? Scientists have proven that cannabis does have medical usefulness, and the more we learn the more intriguing these discoveries become. Since the early 1980s, medical researchers have published about how cannabis relieves pressure in the eye, thus easing the symptoms of glaucoma, a disease that causes blindness. THC is also "neuroprotective," meaning in essence that it prevents brain damage. Some studies have suggested that cannabis could mitigate the effects of Alzheimer's for this reason.
At the same time, we know that THC interferes with memory, and it's still uncertain what kinds of long-term effects the drug could have on memory functioning. No one has been able to prove definitively that it does or does not erode memory strength over time. Obviously, smoking it could cause lung damage. And, like the legal intoxicant alcohol, cannabis can become addictive.
Should cannabis be illegal, while alcohol flows? Unfortunately that's not the kind of question that science can answer. Let's leave the moral questions to courts, policymakers and shamans. I'll be off to the side, smoking a joint, thinking about my acetylcholine system and the many uses of the hippocampus.
Police in downtown Los Angelese are fighting crime by predicting offences - before they have even happened.
Unlike the usual method of responding to 911 calls, cops use computers which show them 'red spots' where an incident is most likely to occur.
They are then deployed onto the streets in a bid to deter thugs, burglers and gangsters from going on their next crime spree.
Technical: LAPD cops study an enormous computer screen showing 'red spots' where the next crime is most likely to committed
The 'predictive policing' system pulls together crime statistics and pinpoints the areas where most offences are being carried out. Police are then sent to patrol those streets
The programme has some similarities with the hit science fiction film Minority Report. The movie is set in 2054 and a special police unit is able to arrest murderers before they commit their crimes.
However, unlike LAPD's system who use computer data, those in Minority Report employ special psychics called 'precogs'.
Tom Cruise plays 'PreCrime' captain John Anderton but the system eventually predicts that he will commit a future murder and he has to take flight.
Such disturbing situations are unlikely to happen with LAPD's system, which uses crime statistics - and not premonitions - to pinpoint the next likely incident.
The system has been trialled in the Foothill division of downtown LA since November and could be rolled out to other areas if it is successful
The 'predictive policing' system being used in the Foothill Division of downtown LA has been developed from the same kind of mathematical calculations used to predict earthquakes and aftershocks.
It analyses the times, dates, and places of recent crimes such as burglaries, break-ins, and car thefts. It also looks at the frequency of offences and predicts how many are likely to be carried out if the trend continues.
If a spate of crimes have happened in one area, or a crook appears to be moving across the region, this is flagged up the software. The data is then aggregated and 'hot spots' are formed.
Capt. Sean Malinowski says the system is able to put police on the streets before crimes have happened.
Futuristic: Tom Cruise, left, as John Anderton in the science fiction hit Minority Report, which uses psychic 'precogs' to predict future crimes
Complex: Anderton uses his special powers to predict crime to map future offenders on a giant computer screen. The premonitions backfired when he was himself accused of a future murder
'Sixty-five percent of our crimes are burglary, grand theft auto and burglary from a motor vehicle. And that's what these boxes represent,' he told CBS.
Los Angeles Police Chief Charlie Beck said the main goal was to prevent crime. Since the system was introduced burglaries are down 33 per cent and violent crime is also down 21 per cent.
Police Chf Beck said: 'I love catching people - it's what I live for - but what I'd rather do is live in a place and work in a place where crime didn't happen.
'Everybody thinks they do their profession as well as it can be done and so they don't need any help. If this old street cop can change the way that he thinks about these things, then I know my kids can do the same.'
He added that the system helps police to use their officers more effectively. It has been tested in the Foothill Division since last November and if it is found to be successful it could be roled out across more divisions in LA.
jailed British terrorist has had his sentence cut by two years in a supergrass deal after giving evidence about an al Qaeda-linked “martyrdom” plot in New York, it was revealed today. Former teacher Saajid Badat was jailed for 13 years in 2005 for plotting with shoe bomber Richard Reid to blow up a transatlantic airliner in 2001 in what an Old Bailey judge said was a “wicked and inhuman” plot. He has now had his term reduced by two years under the first “supergrass” deal involving a terror convict, after providing intelligence to US prosecutors investigating an alleged plot to blow up the New York subway on the eighth anniversary of the 9/11 attack. Details of the deal — kept secret for more than two years — were revealed today by the Crown Prosecution Service as a trial of the alleged al Qaeda plotters began in New York. Defendant Adis Medanjanin, a 27-year-old Bosnian-born US citizen, is charged with conspiring to use a weapon of mass destruction, conspiring to commit murder in a foreign country, and providing “material support” to al Qaeda. He is said to have had terrorist training in Pakistan in 2008 and then returned to begin a plot to use beauty parlour chemicals to blow up the subway. Badat, from Gloucester, joined Reid’s shoe bomb conspiracy but pulled out at the last minute.
Gunmen have launched multiple attacks across the Afghan capital Kabul. Western embassies in the heavily-guarded, central diplomatic area are understood to be among the targets as well as the parliament building in the west. There are reports that up to seven different locations have been hit. The Taliban has admitted responsibility, saying their main targets were the British and German embassies. There is no word at this stage on any casualties.
Hundreds of prisoners are believed to have escaped from a jail in northwest Pakistan after it was attacked by anti-government fighters armed with guns and rocket-propelled grenades. Some of those who escaped from the facility in the town of Bannu, in the Khyber Pakhtunkhwa province, early on Sunday morning were "militants", an intelligence official told the Reuters news agency. "Dozens of militants attacked Bannu's Central Jail in the early hours of the morning, and more 300 prisoners have escaped," Mir Sahib Jan, the official, said. In Depth Profile: Pakistani Taliban "There was intense gunfire, and rocket-propelled grenades were also used." Many of those who escaped following the raid were convicted Tehreek-e-Taliban Pakistan (TTP) fighters, Al Jazeera's Kamal Hyder reported from Lahore. A prison official in Bannu confirmed that "384 prisoners have escaped". A police official identified one of the inmates who escaped as a "dangerous prisoner", who took part in one of the attempts to kill the former president, Pervez Musharraf. The TTP, an umbrella organisation for anti-government groups that are loosely allied with the Taliban in Afghanistan and al-Qaeda, took responsibility for the attack. A spokesman for Hakeemullah Mehsud, TTP's leader, confirmed to Al Jazeera that the group was responsible for the attack. Another Taliban spokesman told Reuters: "We have freed hundreds of our comrades in Bannu in this attack. Several of our people have reached their destinations, others are on their way.". Our correspondent said the attack took place in the early morning and had resulted in an exchange of fire that had left several people wounded. "After the attack the paramilitary and regular military forces came to that location and tried to surround the area," he said. "They have arrested up to a dozen men, but most of the people have indeed escaped." The injured were rushed to a local hospital in Bannu. Sources told Al Jazeera that as many as 150 fighters were involved in the attack. After blowing up the gates of the main prison at around 1:30am local time (20:30 GMT on Saturday), they entered the compound and freed the inmates, the sources said. The attackers had arranged for the transportation of the inmates from the facility. A police official told Reuters that Bannu's Central Jail held 944 prisoners in total, and that six cell blocks had been targeted in the attack.
Sales of the two most popular prescription painkillers in the United States have exploded in new parts of the country, an Associated Press analysis shows, worrying experts who say the push to relieve patients' suffering is spawning an addiction epidemic. Drug Enforcement Administration figures show dramatic rises between 2000 and 2010 in the distribution of oxycodone, the key ingredient in OxyContin, Percocet and Percodan. Some places saw sales increase sixteenfold. Meanwhile, the distribution of hydrocodone, the key ingredient in Vicodin, Norco and Lortab, is rising in Appalachia, the original epicenter of the U.S. painkiller epidemic, as well as in the Midwest. The increases have coincided with a wave of overdose deaths, pharmacy robberies and other problems in New Mexico, Nevada, Utah, Florida and other states. Opioid pain relievers, the category that includes oxycodone and hydrocodone, caused 14,800 overdose deaths in 2008 alone, and the death toll is rising, the Centers for Disease Control and Prevention says. Across the U.S., pharmacies received and ultimately dispensed the equivalent of 69 tons of pure oxycodone and 42 tons of pure hydrocodone in 2010, the last year for which statistics are available. That's enough to give 40 5-mg Percocets and 24 5-mg Vicodins to every person in the United States. The DEA data records shipments from distributors to pharmacies, hospitals, practitioners and teaching institutions. The drugs are eventually dispensed and sold to patients, but the DEA does not keep track of how much individual patients receive. The increase is partly due to the aging U.S. population with pain issues and a greater willingness by doctors to treat pain, said Gregory Bunt, medical director at New York's Daytop Village chain of drug treatment clinics. Sales are also being driven by addiction, as users become physically dependent on painkillers and begin "doctor shopping" to keep the prescriptions coming, he said. "Prescription medications can provide enormous health and quality-of-life benefits to patients," Gil Kerlikowske, the U.S. drug czar, told Congress in March. "However, we all now recognize that these drugs can be just as dangerous and deadly as illicit substances when misused or abused." Opioids like hydrocodone and oxycodone can release intense feelings of well-being. Some abusers swallow the pills; others crush them, then smoke, snort or inject the powder. Unlike most street drugs, the problem has its roots in two disparate parts of the country -- Appalachia and affluent suburbs, said Pete Jackson, president of Advocates for the Reform of Prescription Opioids. "Now it's spreading from those two poles," Jackson said. A few areas that include military bases or Veterans Affairs hospitals have seen large increases in painkiller use because of soldier patients injured in the Middle East, law enforcement officials say. Experts worry painkiller sales are spreading quickly in areas where there are few clinics to treat people who get hooked, Bunt said. In Utica, New York, Patricia Reynolds has struggled to find treatment after becoming dependent on hydrocodone pills originally prescribed for a broken tailbone. The nearest clinics offering Suboxone, an anti-addiction drug, are an hour's drive away in Cooperstown or Syracuse. And those programs are full and are not accepting new patients, she said. "You can't have one clinic like that in the whole area," Reynolds said. "It's a really sad epidemic. I want people to start talking about it instead of pretending it's not a problem and hiding."
CONVICTED drug smuggler Schapelle Corby last night said she was "too scared to get my hopes up" after Indonesia's Justice and Human Rights Ministry recommended her jail sentence be slashed by 10 years - meaning she could be back in Australia within weeks. Her family is now anxiously awaiting a decision by Indonesian President Susilo Bambang Yudhoyono, who will have the final say on whether Corby is released. From her cell at Bali's Kerobokan prison, Corby last night said she was waiting for more information about the ministry's recommendation. Her sister Mercedes, who was visiting Schapelle when the news broke, said that if Dr Yudhoyono did agree to cut 10 years from Corby's sentence, she would be eligible to go home immediately. "She will have done eight years in October, plus she's had two years reduced in good behaviour, so that's 10 years," she said. "So if another 10 years is cut, she should be pretty much eligible for release immediately." Mercedes said, if released, her sister planned to head straight back to Australia to live with her mother Rosleigh in Queensland. Corby was jailed for 20 years in 2004 for attempting to smuggle 4.1kg of marijuana into Bali in a body board bag. The announcement of the major breakthrough in the former Gold Coast beautician's drug saga came as a "pleasant shock" to Corby and her family yesterday when The Daily Telegraph told them of the ministry's recommendation. Mercedes was at the prison having a small birthday celebration with Schapelle for their younger sister Mele, who had just turned 22. "Oh wow, have they recommended clemency? I hope this is true. I better make some calls," she said. A few hours later Mercedes said the family was "too nervous" to get their hopes up and would await the President's ruling before they celebrated. Corby first launched her bid for clemency two years ago, appealing for an early release on the grounds she was suffering from mental illness which could endanger her life. "She's on anti-psychotics to keep her stable, but she goes up and down," Mercedes said. A Justice Ministry official yesterday revealed the recommendation to slash Corby's sentence was based on humanitarian grounds: "Our office agreed with her clemency. We recommended granting it." Corby's lawyer Iskander Nawing described it as a "huge development" and a breakthrough. The recommendation also includes an approval for clemency from the director-general of prisons. Dr Yudhoyono's decision will be based on the recommendation from the Justice Ministry, as well as advice from the Attorney-General's Department, Foreign Ministry and National Narcotics Board. Print
Drug paraphernalia and a white powdery substance were discovered in Whitney Houston's hotel room on the day she died, according to a coroner. The full report says the 48-year-old was found on 11 February lying face down in an overflowing hotel bathtub. Investigators said they recovered a rolled-up piece of paper, a small spoon and a portable mirror in the bathroom. The autopsy concluded that the singer had drowned due to the effects of cocaine use and heart disease. The report also indicated the singer had a perforated nose, a sign of long-term substance abuse. The 42-page document gave more details than an initial report released last month. Houston was found dead hours before she was due to attend a pre-Grammy party. One of the world's best known singers in the 1980s and 1990s, Houston had a long battle with drug addiction. Friends and family have said she appeared committed to a comeback, including a new film, during the time before her death.
The British government wants to expand its powers to monitor email exchanges and website visits, The Sunday Times reported. Internet companies would be instructed to install hardware to allow the Government Communications Headquarters (GCHQ) to go through "on demand" every text message and email sent, websites accessed and phone calls made "in real time, the paper said. The plans are expected to be unveiled next month. The Home Office said ministers were preparing to legislate "as soon as parliamentary time allows" but said the data to be monitored would not include content. "It is vital that police and security services are able to obtain communications data in certain circumstances to investigate serious crime and terrorism and to protect the public," a spokesman said. "We need to take action to maintain the continued availability of communications data as technology changes. "Communications data includes time, duration and dialling numbers of a phone call, or an email address. "It does not include the content of any phone call or email and it is not the intention of government to make changes to the existing legal basis for the interception of communications." An attempt to bring in similar measures was abandoned by the Labour government in 2006 amid strong opposition. However, ministers in the Conservative-Liberal Democrat coalition government believe it is essential that the police and security services have access to such communications data in order to tackle terrorism and protect the public. The plans would not allow GCHQ to access the content of communications without a warrant. However, they would enable the agency to trace whom a group or individual had contacted, how often and for how long, the report said.
Eight people from 'Holy Death' cult arrested in Mexico over ritual sacrifices of woman and two 10-year-old boys
Eight people have been arrested in northern Mexico have over the killing of two 10-year-old boys and a woman in what appears to be ritual sacrifices. Prosecutors in Sonora, in the north-west of the country have accused the suspects of belonging to the La Santa Muerte (Holy Death) cult. The victims' blood has been poured round an altar to the idol, which is portrayed as a skeleton holding a scythe and clothed in flowing robes. The cult, which celebrates death, has been growing rapidly in Mexico in the last 20 years, and now has up to two million followers. Jose Larrinaga, spokesman for Sonora state prosecutors, said the most recent killing was earlier this month, while the other two were committed in 2009 and 2010. Their bodies were found at the altar site in the small mining community of Nacozari, 70 miles south of Douglas, Arizona. Investigations were launched after the family of 10-year-old Jesus Octavio Martinez Yanez reported him missing early this month.
Dispute among gang members at a North Miami-area funeral home sparked a mass shooting that injured 12 people and killed two men, according to Miami-Dade police and law enforcement. The gunmen, who fired a barrage of bullets at a crowd of mourners Friday night, remained on the loose. Investigators have not released information about the shooters, only that a white car may have been involved. One of the victims, a 43-year-old man, died outside the Funeraria Latina Emanuel funeral home, authorities said. The other, a 27-year-old man, died at the hospital. Witnesses at the funeral home had said one of the two people killed was shot in the chest. Among the wounded was a 5-year-old girl who was shot in the leg. She is hospitalized at Jackson Memorial Hospital and is listed in stable condition. The funeral was for Morvin Andre, 21, of North Miami, who was buried Saturday morning at Southern Memorial Park next to the funeral home. Andre was killed March 16 after he tried to jump 22-and-a-half feet from the fourth floor of the Aventura Mall parking garage to escape pursuit from Bloomingdale’s loss prevention employees. Andre landed on his feet, but then fell back and hit his head, according Aventura Police Major Skip Washa, a spokesman. Washa said Saturday the county medical examiner’s office has ruled Andre’s death a suicide because the Bloomingdale’s employees were one floor below Andre when they told him to stop. Instead, he jumped. Originally, it was reported that Andre, a nursing student at Broward Community College, had been killed in a shooting, according to mourners at the funeral home. A law enforcement official told the Miami Herald that the shooting involved members of several South Florida gangs who were in attendance at his wake Friday night to pay their respects. Andre was not part of a gang himself, the official said. Certain gang members took offense when someone touched Andre’s body in the casket, setting off an argument that spilled out into the street. Members of one gang retrieved an assault rifle and a handgun from a car and opened fire at other gang members in front of the funeral home, a police commander told Miami Herald news partner WFOR-CBS 4. Shooting erupted as more than 100 people were gathered outside the funeral home, in the 14900 block of West Dixie Highway, outside the city limits of North Miami. “I was on my way out of the chapel when I heard the shots,“ said A.D. Lenoir, the pastor who officiated at the service. “I told people to look for cover. It was chaos.” Lenoir, 29, said people were screaming, crying and yelling. Several victims were taken to Jackson, and others to local hospitals. The West Dixie Highway corridor has been the scene of several shootings in recent years. In 2007, the owner of a martial arts studio was fatally gunned down in a drive-by.
A Kansas man was struck by lightning hours after buying three Mega Millions lottery tickets on Thursday, proving in real life the old saying that a gambler is more likely to be struck down from the sky than win the jackpot. Bill Isles, 48, bought three tickets in the record $656 million lottery Thursday at a Wichita, Kansas grocery store. On the way to his car, Isles said he commented to a friend: "I've got a better chance of getting struck by lightning" than winning the lottery. Later at about 9:30 p.m., Isles was standing in the back yard of his Wichita duplex, when he saw a flash and heard a boom -- lightning. "It threw me to the ground quivering," Isles said in a telephone interview on Saturday. "It kind of scrambled my brain and gave me an irregular heartbeat." Isles, a volunteer weather spotter for the National Weather Service, had his portable ham radio with him because he was checking the skies for storm activity. He crawled on the ground to get the radio, which had been thrown from his hand. Isles had been talking to other spotters on the radio and called in about the lightning strike. One of the spotters, a local television station intern, called 911. Isles was taken by ambulance to a hospital and kept overnight for observation. Isles said doctors wanted to make sure his heartbeat was back to normal. He suffered no burns or other physical effects from the strike, which he said could have been worse because his yard has a power line pole and wires overhead. "But for the grace of God, I would have been dead," Isles said. "It was not a direct strike." Isles said he had someone buy him ten more tickets to the Mega Millions lottery on Friday night. While one of the three winning tickets was sold in Kansas, Isles was not a winner. Officials of the Mega Millions lottery, which had the largest prize in U.S. history, said that the odds of winning lottery were about 176 million to one. Americans have a much higher chance of being struck by lightning, at 775,000 to one over the course of a year, depending on the part of the country and the season, according to the National Weather Service. Isles, who is out of work after being laid off last June by a furniture store, said he did once win $2,000 in the lottery and will keep playing. "The next time I will use the radio while sitting in the car," he said